SSSD 2023

57th Annual Meeting of the Scandinavian Society for the Study of Diabetes (SSSD2023) in Aarhus

The registration for the 57th Annual Meeting of the Scandinavian Society for the Study of Diabetes (SSSD2023) in Aarhus, Denmark is now open https://ddeacademy.dk/events/57th-annual-meeting-scandinavian-society-study-diabetes-sssd2023. The Annual Meeting will be held 24-26 May 2023 at the new Steno Diabetes Center Aarhus.

We encourage all researchers/clinicians working within any field of diabetes to participate. Participants are encouraged to submit abstracts, and participation is guaranteed for all who have submitted an abstract. All accepted abstracts will be presented orally with two Outstanding Presentation Awards each of 5000 NOK awarded to the two best presentations.

The program will alternate between invited talks within different areas of diabetes research (complications, epidemiology, appetite regulation, adipose tissue, glucagon, lifestyle interventions), and short oral presentations from participants.

Priority will be given to networking and social events, which will be incorporated throughout the meeting, to facilitate and strengthen collaborative relationships. During the meeting, the annual SSSD research prizes are awarded with presentations from the prize recipients (Knud Lundbæk Award, SSSD Young Investigator Award, Novo Nordisk Foundation Lecture Prize and The Swedish Child Diabetes Foundation Nordic Prize).

Public Defence January 19: Archana Sharma

Cand.med. Archana Sharma at Institute of Clinical Medicine will be defending the thesis “Glucose metabolism in South Asian and Nordic women with previous gestational diabetes mellitus” for the degree of PhD (Philosophiae Doctor).

Time and place: Jan. 19, 2023 12:15 PM, Store auditorium (Frontbygget), Akershus Universitetssykehus, Sykehusveien 25, Lørenskog

For more information, click Public Defence: Archana Sharma - Institute of Clinical Medicine (uio.no)

Important novel data from the EPIPREG study presented in the prestigious journal Diabetes

With data from the EPIPREG sample, we identified six cross-ancestry CpG sites related to insulin resistance in pregnancy, whereof five were replicated in independent studies. From methylation quantitative trait loci analysis, we identified gene variants related to all five replicated cross-ancestry CpG sites, which were associated with several cardiometabolic phenotypes. Mediation analyses suggested that the gene variants regulate insulin resistance through DNA methylation.

DIABETES, December 19th 2022, online ahead of print: Click here

Lifetime risk, life expectancy, and years of life lost to type 2 diabetes in 23 high-income jurisdictions: a multinational, population-based study

Using data from 24 population-based data sources from Europe, Asia, North America, and Oceania, we estimated the lifetime risk of type 2 diabetes, life expectancy in people with and without type 2 diabetes, and years of life lost to type 2 diabetes. With the incidence of type 2 diabetes declining in the high-income setting, there has been a corresponding decrease in lifetime risk in many high-income jurisdictions.

However, the burden of diabetes remains high. This substantial individual burden should be considered in future public health strategy and emphasised in patient counselling to improve health outcomes for people with type 2 diabetes.

THE LANCET Diabetes and Endocrinology VOLUME 10, ISSUE 11, NOVEMBER 01, 2022

Sindre Lee Ødegård (post-doc) får stipend fra Norsk endokrinologisk Forening

Astra-Zeneca og Norsk Endokrinologisk Forening har lyst ut forskningsmidler ment for å stimulere klinisk forskning i Norge innen terapiområdet diabetes.

Post-doc Sindre Lee-Ødegård ved UiO har søkt om midler for å gjennomføre proteom-kartlegging hos 60 personer med risiko for type 2 diabetes (kvinner av sør-asiatisk eller nordisk opprinnelse med tidligere svangerskapsdiabetes) med mål om å forbedre patofysiologisk forståelse, risiko-stratifisering og identifikasjon av mulige nye behandlingsmål/intervensjonsmuligheter. Prosjektet fremstår å være gjennomførbart, hvor søker kommer fra et faglig sterkt miljø og har en solid publikasjonsliste.

Tematisk tilhører prosjektet et spennende felt innen presisjonsmedisin, med potensiale for nye funn som på sikt kan ha klinisk nytte.

Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study

The team behind the DiViD study previously reported the presence of enterovirus (EV) genome and proteins in pancreatic sections from six live newly diagnosed patients with type 1 diabetes. In this issue, Krogvold et al (https://doi.org/10.1007/s00125-022-05779-2) confirm the presence of EVs and also demonstrate that no other common human viruses are present in the pancreases of the six DiViD cases.

The authors demonstrate that the EV strains detected represent live infectious viruses capable of establishing a persistent pancreatic infection. As previously shown in persistent EV infection of the heart, persistent EV infection of the pancreas could lead to progressive tissue-specific dysfunction. The authors conclude that the early phase of type 1 diabetes is associated with low-grade EV infection. They go on to suggest that the findings strengthen the need for studies exploring the potential benefits of enteroviral vaccines for individuals at high risk of developing type 1 diabetes and antiviral treatment for individuals in the early phase of type 1 diabetes