Top-Cited Study in Acta Physiologica 2022-2023

We are proud to announce that a new study from the Sindre Lee-Ødegård and the MyoGlu group has been recognized as one of the top ten most cited articles in Acta Physiologica for the period 2022–2023. Acta Physiologica is renowned as the highest-ranked journal in the field of physiology, making this recognition an outstanding achievement.

Study Highlights

The study aimed to deepen the understanding of cardiometabolic disease biomarkers by exploring how exercise regulates circulating microRNAs (miRNAs) in extracellular vesicles (EVs). The researchers investigated the links between EV-derived miRNAs and gene expression in skeletal muscle and fat tissue during exercise. Key findings include:

• Exercise boosts the levels of various circulating miRNAs within EVs.

• Two miRNAs, miR-32-5p and miR-339-3p, were noted for their connection to inflammation and mitochondrial function in fat tissue, highlighting their potential as biomarkers for metabolic issues.

• Although there is ongoing debate about the abundance of miRNAs within EVs, this research underscores their crucial role in cell communication and their potential in diagnosing and understanding cardiometabolic diseases.

Editorial Mention

In addition to being highly cited, the study was also featured in its own editorial mention.